Objective:　To　investigate　a　simple,　safe,　and　effective　surgical　approach　to　treat　vascular　malformations　(VM).　Methods:　Tissues　of　vein,　heart,　liver,　and　kidney　were　obtained　and　pathologically　observed　from　30　rabbits　whose　central　veins　of　the　ears　were　retained　with　copper　needles,　and　the　concentration　of　CU2+　in　serum　was　measured.　In　the　clinical　research,　3　methods　were　employed　to　treat　89　patients　with　VM:　(1)　retaining　copper　needles　alone;　(2)　ligaturing　lesions　and　retaining　copper　needles;　(3)　retaining　copper　needles　charged　with　direct　current　(DC).　Results:　After　the　treatment　of　retaining　copper　needles,　thrombus,　fibrosis,　and　necrosis　of　the　malformed　vein　walls　gradually　increased.　The　effective　rate　was　95.5%.　Conclusion:　Treatment　with　copper　needles　retained　in　malformed　blood　vessels　leads　to　denaturalization,　fibrosis,　and　disappearance　of　the　blood　vessel　structure,　and　thus　it　is　an　effective　way　to　treat　VM.