In　this　paper,　we　study　the　effect　of　stimulation　of　the　genioglossus　with　percutaneous　biphasic　electrical　pulses　on　patients　with　the　obstructive　sleep　apnea　syndrome　(OSAS).　The　experiment　was　conducted　in　22　patients　clinically　diagnosed　with　OSAS.　The　patients　were　monitored　with　polysomnography　(PSG)　in　the　trial.　When　the　sleep　apnea　was　detected,　the　genioglossus　was　stimulated　with　percutaneous　biphasic　electrical　pulses　that　were　automatically　regulated　by　a　microcontroller　to　achieve　the　optimal　effect.　The　percutaneous　biphasic　electrical　stimulation　caused　contraction　of　the　genioglossus,　forward　movement　of　the　tongue,　and　relieving　of　the　glossopharyngeal　airway　obstruction.　The　SaO(2),　apnea　time,　hypoxemia　time,　and　change　of　respiratory　disturbance　index　(RDI)　were　compared　in　patients　with　treatment　and　without　treatment.　With　percutaneous　biphasic　electrical　stimulation　of　the　genioglossus,　the　OSAS　patients　showed　apnea　time　decreased　(P　＜　0.01),　RDI　decreased　(P　＜　0.01),　and　SaO(2)　increased　(P　＜　0.01).　No　tissue　injury　or　major　discomfort　was　noticed　during　the　trial.　The　stimulation　of　genioglossus　with　percutaneous　biphasic　electrical　current　pulse　is　an　effective　method　for　treating　OSAS.