We　investigate　the　influence　of　the　transverse　mode　of　the　pump　beam　and　the　geometry　of　the　pump-probe　configuration　on　the　femtosecond　two-photon　excitation　transient　absorption　(TA)　spectroscopy.　Strong　modulation　of　the　transient　TA　dynamics　may　result　from　the　multi-peak　distribution　of　the　transverse　mode　of　the　pump　beam,　the　large　pump　beam　size,　and　the　large　separation　angle　between　the　pump　and　the　probe　beams,　which　is　sensitive　to　the　pulse　length.　Quantitative　characterization　of　this　kind　of　spatial　effect　is　of　general　importance　for　the　correct　interpretation　of　the　photophysical　mechanisms　that　can　be　revealed　by　the　two-photon　TA　measurements.