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作者:

Qiao, Aike (Qiao, Aike.) (学者:乔爱科) | Matsuzawa, Teruo (Matsuzawa, Teruo.)

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Scopus SCIE

摘要:

The effectiveness of femoral bypass grafts is correlated with the geometric configuration and hemodynamics of the bypass and the arteries. As an attempt to develop a new design for femoral bypass grafts, we present a novel geometric configuration for a symmetrically implanted 2-way bypass graft. In order to investigate how the symmetric 2-way bypass grafts affect the flow patterns through the anastomosis, physiologic blood flows in 1-way and 2-way models for a fully stenosed femoral bypass were simulated with the finite element method, and the hemodynamic factors in these models were studied. The temporal and spatial distributions of flow patterns and wall shear stresses in the vicinity of distal anastomosis during the cardiac cycle were analyzed. The results computed showed that the 2-way model has more preferable hemodynamics than the 1-way model in the distribution of flow patterns and wall shear stresses, and it may improve the flow conditions and decrease the probability of restenosis. However, the limitations of the 2-way bypass model may counteract the positive effects. More detailed hemodynamic studies are necessary to fully assess the viability of the 2-way bypass graft.

关键词:

anastomosis biomechanics intimal hyperplasia restenosis wall shear stress

作者机构:

  • [ 1 ] Beijing Univ Technol, Coll Life Sci & Med Engn, Beijing 100022, Peoples R China

通讯作者信息:

  • 乔爱科

    [Qiao, Aike]Beijing Univ Technol, Coll Life Sci & Med Engn, Beijing 100022, Peoples R China

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来源 :

BIORHEOLOGY

ISSN: 0006-355X

年份: 2007

期: 2

卷: 44

页码: 103-124

1 . 1 0 0

JCR@2022

ESI学科: MOLECULAR BIOLOGY & GENETICS;

JCR分区:3

被引次数:

WoS核心集被引频次: 4

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ESI高被引论文在榜: 0 展开所有

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