收录：
摘要：
A QM-MM calculation was carried out to study the mechanism of DNA cleavage by the dipeptide seryl-histidine (SH). The effective molecular recognition between SH and DNA through multi-hydrogen-bonds was obtained, as well as the corresponding structural parameters. The results could be used to explain the mechanism of DNA cleavage by SH, which supposed that the formation of penta-coordinate phosphorus intermediate caused the phosphodiester bond hydrolysis.
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电子邮件地址：
来源 ：
ACTA CHIMICA SINICA
ISSN： 0567-7351
年份： 2004
期： 24
卷： 62
页码： 2444-2446
2 . 5 0 0
JCR@2022
ESI学科： CHEMISTRY;
JCR分区：2
