Six　novel　spironolactone-analogs　steroids　(3-8)　were　isolated　from　spironolactone　by　using　various　chromatographic　methods.　Their　structures　were　elucidated　by　spectrometric　analysis.　Two　of　the　analogs　(3　and　7)　were　confirmed　by　X-ray　crystallography.　The　A-ring　of　compounds　3-7　is　opened　at　C-2-C-3　bond,　and　compound　7　is　an　organic　polysulfide,　which　has　a　rare,　nine-membered　ring　with　a　five　sulfur　atom　bridge.　(C)　2004　Published　by　Elsevier　Inc.