By　using　computer　modelling　based　on　the　lattice　energy　minimization　technique,　the　lattice　energies　of　nineteen　types　of　aluminophosphate　molecular　sieves　have　been　calculated.　The　studies　on　the　relationship　between　the　topological　structures　of　these　molecular　sieves　and　framework　lattice　energies　have　been　performed　by　monovariate,　multivariate　regression　analysis　and　standard　back-propagation　(BP)　algorithm　of　artifical　neural　networks.　The　predicted　results　by　using　multiregression　analysis　are　in　agreement　with　the　calculated　lattice　energies　and　show　a　good　multivariate　linear　relationship　between　the　coordination　sequences　((N)　over　bar(2)　similar　to　(N)　over　bar(3))　of　these　molecular　sieves　and　framework　lattice　energies,　The　lattice　energies　of　ten　types　of　the　topological　structures　have　been　predicted.