The　W-La2O3-Y2O3-ZrO2　materials　were　prepared　by　vacuum　hot　pressing　sintering　process.　The　microstructure　was　characterized　by　scanning　electron　microscopy　(SEM).　The　effects　of　sintering　temperature,　sintering　pressure,　holding　time　and　heating　rate　on　relative　density,　hardness　and　microstructure　were　studied.　The　sintering　activation　energy　of　the　powder　was　calculated.　Based　on　the　result,　the　best　sintering　parameters　by　vacuum　hot　pressing　sintering　are　as　follows:　sintering　temperature　of　1600　degrees　C,　sintering　pressure　of　60　MPa　and　holding　time　of　60　min.　The　heating　rate　is　10　degrees　C　center　dot　min(-1)　from　room　temperature　to　1000　degrees　C　and　4　degrees　C.min(-1)　from　1000　to　1600　degrees　C.　Using　this　process,　the　grain　size　is　about　3　mu　m　in　diameter　with　relative　density　at　99.7%,　and　the　hardness　is　HV　528.5.　The　sintering　characteristic　index　(n)　of　the　specimen　is　4,　and　the　sintering　mechanism　mainly　depends　on　the　diffusion　from　the　surface　to　the　intragranular　in　the　volume　diffusion.　The　sintering　activation　energy　of　W-La2O3-Y2O3-ZrO2　material　is　286.2　kJ.mol(-1),　which　indicates　that　the　powder　has　higher　activity　in　sintering　process.　Graphic　abstract