We　systematically　investigated　the　local　crystallographic　texture,　magnetic　domain　structure,　and　the　associated　magnetic　reversal　process　of　different　regions,　namely　fine-grain　(FG),　coarse-grain　(CG),　and　large-grain　(LG)　regions　in　hot-deformed　Nd-Fe-B　magnets.　The　FG　region　possesses　the　strongest　(00　1)　texture　and　plays　a　dominant　role　on　the　magnetic　properties.　In　contrast,　the　CG　region　with　partially　aligned　sub-micron　grains　and　the　LG　region　with　randomly　aligned　micro-sized　grains　exhibit　much　weaker　(00　1)　texture,　where　the　reversal　magnetic　domains　primarily　nucleate,　deteriorating　the　remanence　and　the　squareness　of　the　demagnetization　curve　seriously.　This　finding　highlights　a　new　strategy　to　achieve　high　energy　density　in　hotdeformed　Nd-Fe-B　magnets,　i.e.　maximizing　the　volume　fraction　of　highly　(00　1)　textured　FG　regions　and　reducing　the　undesirable　CG　and　LG　regions.　Our　further　experiment　enhancing　the　maximum　energy　product　of　the　magnet　from　42.6　to　51.1　MGOe　through　optimizing　the　microstructure　homogeneity　unambiguously　demonstrates　the　general　applicability　of　the　strategy.