The　effect　of　thermo-mechanical　deformation　on　the　microstructure　was　investigated　by　isothermal　compression　and　microstructure　characterization.　The　mechanical　response　of　as-casted　Ti-6.2Al-3Sn-5Zr-0.5Mo-1.0Nb-0.4Si-0.2Er　titanium　alloy　was　sensitive　to　the　deformation　temperatures　and　strain　rates.　The　true　stress　increased　with　the　increase　in　the　strain　rate　and　decreased　in　temperature.　The　discontinuous　dynamic　recrystallization　of　beta　phase　was　promoted　with　the　increase　in　temperatures.　Global　a　phase　generated　during　the　deformation　at　a　temperature　of　980　degrees　C.　The　(Ti,　Zr)(3)Si　and　participated　phase　were　dissolved　into　the　matrix　above　950　degrees　C,　which　acted　as　the　homogenizing　annealing　process.　However,　novel　participated　phases　with　an　average　diameter　of　20　nm　generated.yyy