A　long-span　concrete-filled　steel　tubular　(CFST)　arch　bridge　suffers　severe　vehicle-induced　dynamic　responses　during　its　service　life.　However,　few　quantitative　studies　have　been　reported　on　the　typical　diseases　suffered　by　such　bridges　and　their　effects　on　vehicle-induced　dynamic　response.　Thus,　a　series　of　field　tests　and　theoretical　analyses　were　conducted　to　study　the　effects　of　typical　diseases　on　the　vehicle-induced　dynamic　response　of　a　typical　CFST　arch　bridge.　The　results　show　that　a　support　void　results　in　a　height　difference　between　both　sides　of　the　expansion　joint,　thus　increasing　the　effect　of　vehicle　impact　on　the　main　girder　and　suspenders.　The　impact　factor　of　the　displacement　response　of　the　main　girder　exceeds　the　design　value.　The　variation　of　the　suspender　force　is　significant,　and　the　diseases　are　found　to　have　a　greater　effect　on　a　shorter　suspender.　The　theoretical　analysis　results　also　show　that　the　support　void　causes　an　obvious　longitudinal　displacement　of　the　main　girder　that　is　almost　as　large　as　the　vertical　displacement.　The　support　void　can　also　cause　significant　changes　in　the　vehicle-induced　acceleration　response,　particularly　when　the　supports　and　steel　box　girder　continue　to　collide　with　each　other　under　the　vehicle　load.