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作者:

Peng, Kun (Peng, Kun.) | Qiao, Aike (Qiao, Aike.) (学者:乔爱科) | Wang, Junjie (Wang, Junjie.) | Ohta, Makoto (Ohta, Makoto.) | Cui, Xinyang (Cui, Xinyang.) | Mu, Yongliang (Mu, Yongliang.)

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EI SCIE

摘要:

Biodegradable zinc alloy stents offer a prospective solution to mitigate incompatibility between artery and permanent stents. However, biodegradable stents are restricted in clinical therapy mainly because of their insufficient support for opening of stenotic vessel. As an effort to resolve this challenging problem, a novel structure of zinc alloy stent which significantly enhanced scaffold performance is proposed in this paper. Subsequently, the functionality of the new stent on reshaping vessels with 40% of stenosis was investigated in contrast with a common stent via finite element analysis. The simulation results show that radial recoiling ratio and dog-boning ratio of the new stent are decreased by 43.2% and 16.3%, respectively, compared with those of the common stent. A larger and flatter lumen is found in the plaque-vessel system deployed with the new stent. It suggests that the geometry of stent has strong influence on its mechanical performance. With strong scaffold capability and brilliant effect on reshaping stenotic vessel, the biodegradable zinc alloy stent-based novel structure is highly promised to be an alternative choice in interventional surgeries.

关键词:

Biodegradable stent biomechanics finite element analysis stenosis

作者机构:

  • [ 1 ] [Peng, Kun]Beijing Univ Technol, Beijing 100124, Peoples R China
  • [ 2 ] [Qiao, Aike]Beijing Univ Technol, Beijing 100124, Peoples R China
  • [ 3 ] [Wang, Junjie]Beijing Univ Technol, Beijing 100124, Peoples R China
  • [ 4 ] [Cui, Xinyang]Beijing Univ Technol, Beijing 100124, Peoples R China
  • [ 5 ] [Ohta, Makoto]Tohoku Univ, Sendai, Miyagi 9808577, Japan
  • [ 6 ] [Mu, Yongliang]Northeastern Univ, Shenyang 110819, Liaoning, Peoples R China
  • [ 7 ] [Qiao, Aike]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 Pingleyuan, Beijing 100124, Peoples R China

通讯作者信息:

  • 乔爱科

    [Qiao, Aike]Beijing Univ Technol, Beijing 100124, Peoples R China;;[Qiao, Aike]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 Pingleyuan, Beijing 100124, Peoples R China

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来源 :

JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY

ISSN: 0219-5194

年份: 2020

期: 6

卷: 20

0 . 8 0 0

JCR@2022

ESI学科: MOLECULAR BIOLOGY & GENETICS;

ESI高被引阀值:47

JCR分区:4

被引次数:

WoS核心集被引频次: 2

SCOPUS被引频次: 2

ESI高被引论文在榜: 0 展开所有

万方被引频次:

中文被引频次:

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