In　this　paper,　we　proposed　a　new　efficient　measurement　method　of　the　acoustic　transfer　function　(ATF)　between　a　fixed　source　and　a　predesigned　region.　Measuring　the　ATF　in　reverberant　room　is　a　cumbersome　procedure　in　acoustic　signal　processing,　because　the　ATF　rapidly　varies　with　varying　source　and　receiver　positions　over　the　room.　A　major　problem　in　the　measurement　is　how　to　acquire　the　higher　order　ATF　coefficients　using　a　limited　number　of　microphones.　Based　on　the　general　model　of　ATF,　we　assume　that　the　ATF　is　sparse　in　source　domain,　and　then　acquire　the　higher　order　ATF　coefficients　by　applying　compressed　sensing　techniques.　Simulation　results　demonstrate　that　the　method　is　a　practical　way　of　measuring　the　ATF　over　large　area　with　dramatically　reduced　number　of　microphones.　The　successful　estimation　of　the　ATF　over　a　wide　frequency　range　has　also　been　demonstrated.