Digital　medical　3D　printing　technology　is　a　new　hi-tech　which　combines　traditional　medical　and　digital　design,　computer　science,　bio　technology　and　3D　print　technology.　At　the　present　time　there　are　four　levels　application:　The　printed　3D　model　is　the　first　and　simple　application.　The　surgery　makes　use　of　the　model　to　plan　the　processing　before　operation.　The　second　is　customized　operation　tools　such　as　implant　guide.　It　helps　doctor　to　operate　with　special　tools　rather　than　the　normal　medical　tools.　The　third　level　application　of　3D　printing　in　medical　area　is　to　print　artificial　bones　or　teeth　to　implant　into　human　body.　The　big　challenge　is　the　fourth　level　which　is　to　print　organs　with　3D　printing　technology.　In　this　paper　we　introduced　an　application　of　3D　printing　technology　in　tumor　operation.　We　use　3D　printing　to　print　guide　for　invasion　operation.　Puncture　needles　were　guided　by　printed　guide　in　face　tumors　operation.　It　is　concluded　that　this　new　type　guide　is　dominantly　advantageous.