The　manganese　oxide　(MnO2)　sample　was　synthesized　by　the　reduction　of　KMnO4　by　MnSO4.　Cu　doped　manganese　oxide　materials　have　been　synthesized　by　incorporation　method　and　traditional　wet-impregnation　method.　The　structure　of　the　catalysts　was　characterized　by　X-ray　diffraction　and　N-2　adsorption/desorption　analyses　and　their　catalytic　activities　were　performed　by　catalytic　oxidation　of　CO.　The　doping　Cu　to　manganese　oxide　by　traditional　wet-impregnation　method　result　in　a　significant　drop　of　area,　due　to　the　aggregation　of　copper　oxides　particles.　Loading　Cu　to　manganese　oxide　by　incorporation　method　caused　a　slight　change　in　surface　area　of　the　obtained　Cu/MnO2-Q　catalysts.　The　catalytic　activities　of　Cu/MnO2　samples　strongly　depended　upon　the　used　methods,　among　which　5Cu/MnO2-Q　catalyst,　prepared　by　the　incorporation　method,　was　the　most　efficient　catalyst　towards　the　addressed　reactions.　The　excellent　performance　of　5Cu/MnO2-Q　was　mainly　associated　with　the　good　low-temperature　reducibility,　richest　surface　oxygen　and　broadly　dispersed　copper　oxides　species.