Triple-negative　breast　cancer　is　the　worst　prognosis　in　breast　cancer,　accounting　for　10.0-20.8%　of　all　breast　cancers.　Considering　that　triple-negative　breast　cancer　has　great　heterogeneity　and　very　poor　prognosis,　clinical　medication　guidance　is　in　urgent　need　of　a　more　detailed　classification　of　breast　cancer　itself.　Although　many　researchers　have　been　dedicated　to　the　clustering　of　triple-negative　breast　cancer　and　have　found　possible　targets　based　on　typing,　their　results　are　not　closely　related　to　the　prognosis.　This　paper　utilizes　three　clustering　methods　to　retype　the　patient　data　with　triple-negative　breast　cancer,　and　the　results　show　that　the　triple-negative　breast　cancer　data　could　be　classified　into　two　categories.　Eight　important　genes　and　three　important　clinical　factors　related　to　the　prognosis　of　two　types　of　triple-negative　breast　cancer　have　been　obtained.　These　genes　have　the　following　three　characteristics:　co-expression,　differential　expression　and　interaction.　In　terms　of　breast　cancer　control,　the　prognosis　can　be　controlled　as　much　as　possible　by　regulating　gene　levels,　which　provides　new　directions　and　ideas　for　related　research　on　breast　cancer　prognosis.