The　effects　of　different　carbon　sources　on　the　enrichment　of　2,4,6TCP-degrading　microbes　and　on　reactor　stability　were　was　investigated　using　a　lab-scale　sequencing　batch　reactor　(SBR).　Glucose,　sucrose,　and　starch　were　selected　as　different　carbon　sources　because　of　the　different　molecular　weights.　The　sucrose-fed　activated　sludge　(AS)　exhibited　faster　adaption　and　higher　degradation　rates　for　2,4,6-TCP　in　long-term　operation　and　typical　cycles　compared　to　that　fed　with　glucose　and　starch.　Large　amounts　of　extracellular　polymeric　substance　(EPS;　117.54　mg/gVSS)　were　induced　from　AS　after　adding　starch,　leading　to　a　high　SVI　(191　mL/g)　and　poor　sludge　settling.　This　suggests　that　macromolecular　carbon　sources　might　have　a　detrimental　effect　on　the　reactor　operation.　Moreover,　the　high　removal　efficiency　for　TOC　and　chloride　ions　was　achieved　in　a　typical　cycle　of　all　SBRs,　indicating　that　AS　could　completely　mineralize　2,4,6-TCP.　On　average,　more　than　90%　of　the　COD　could　be　removed　in　all　SBRs　during　long-term　operation.　Glucose,　sucrose,　and　starch　facilitated　the　development　of　a　different　microbial　community　compared　to　the　seeding　sludge,　makingChloroflexi,Actinobacteria,　andProteobacteriathe　dominant　phylum　in　the　corresponding　SBR.　The　microbial　abundance　associated　with　the　metabolism　of　2,4,6-TCP　reached　81.02%　due　to　the　addition　of　sucrose.　The　results　of　this　study　could　provide　a　potential　guide　for　the　effective　selection　of　carbon　sources　in　the　treatment　of　chlorophenol　wastewater.