This　paper　used　both　methods　of　single　parameter　and　Multi-parameter　combination　sensitivity　analysis　in　groundwater　numerical　model　parameter　sensitivity　analysis.　With　the　examples　of　Jiaozuo,　Henan　province,　choosing　coefficient　of　permeability,　porosity　and　longitudinal　dispersion　degree　as　factor,　the　paper　analysis　the　main　controlling　factors　of　contaminant　migration　of　Hexavalent　chromium　in　groundwater.　Single　parameter　sensitivity　analysis　results　show　that　the　permeability　coefficient　gives　largest　impact　to　the　migration　of　hexavalent　chromium.　It　is　positively　correlates　with　groundwater　numerical　model.　The　rest　of　the　parameters　assume　the　inverse　correlation.　Multi-parameter　combination　sensitivity　analysis　results　show　that　the　permeability　coefficient　has　absolute　advantage　among　various　parameter　combinations.　Another　conclusion　is　that　longitudinal　dispersion　degree　affects　smaller　on　the　process　of　hexavalent　chromium　pollutants　migration,　but　the　impact　on　the　final　density　is　bigger.