Microfluidic　synthesis　has　attracted　extensive　attention　due　to　the　ability　for　the　multistep　precise　control　of　the　synthesis　parameters,　continuous　and　reproducible　preparation,　and　its　ease　of　integration.　However,　its　commercial　application　is　still　affected　by　its　low　production　efficiency.　In　this　case,　we　report　a　high-throughput　continuous　flow　synthesis　of　highly　dispersed　PtFeCu/C　nanocatalysts　using　a　metal　microchip　setup　with　four　parallel　channels.　The　high　flow　rate　and　integrated　channels　enabled　improving　the　throughput,　whereby　1.33　g　h(-1)of　catalysts　could　be　achieved　with　the　flow　rate　of　1200　mL　h(-1)under　the　experimental　conditions.　The　as-prepared　PtFeCu/C　exhibited　excellent　performance,　1.94　times　higher　than　Pt/C　for　methanol　oxidation.　More　importantly,　the　yield　of　the　PtFeCu/C　nanocatalysts　could　be　further　increased　through　designing　numerous　parallel　channels,　which　might　provide　a　promising　approach　for　large-scale　commercialization　of　the　catalysts.　Such　a　high-throughput　fabrication　pathway　is　significant　for　the　large-scale　industrial　production　of　nanomaterials.