The　stress-strain　response　at　notch　root　for　notched　specimen　was　computed　by　elastic-plastic　finite　element　analysis　(FEA)　under　multiaxial　loading　for　GH4169.　A　uniform　gouge　length　of　the　specimen　was　selected　as　the　dimension　of　the　FE　model.　The　uniaxial　fatigue　data　were　used　to　describe　the　stress-strain　curve.　One　cycle　is　divided　to　different　load　steps　according　to　phase　difference.　Tension-torsion　strain　cyclic　loading　was　implemented　in　FEA.　Fatigue　crack　initiation　life　was　predicted　by　Smith-Watson-Topper　model,　Shang-Wang　and　Sun-Shang　models　with　the　calculated　stress-strain　data　at　notch　root.　The　result　shows　that　the　three　models　are　suitable　for　life　prediction　of　notched　specimen　under　multiaxial　cyclic　loading　for　GH4169　alloy.