Synergic　management　of　the　local　crop-biomass　coproduction　system　is　the　potential　to　increase　resource　efficiency　and　promote　sustainable　development.　In　this　paper,　an　interval　fuzzy　linear　fractional　programming　(IFLFP)　model　is　developed　for　planning　regional　food　production　with　the　consideration　of　ecological　protection,　water　resource　conservation,　biomass　energy　supply,　and　food-energy-water　(FEW)　nexus.　The　main　advantages　of　the　proposed　IFLFP　model　are　the　abilities　to　reflect　uncertainties　with　different　characters　as　interval　values　and　fuzzy　sets　and　to　provide　system　efficiency　measurement　by　the　ratio　form　of　conflict　objective　functions.　The　IFLFP　model　is　then　tailored　for　the　application　of　the　crop-biomass　coproduction　management　with　FEW　nexus　in　Jiangsu　Province,　China.　The　influences　of　different　optimization　goals　(i.e.　economic　benefits　and　environmental　benefits　per　unit　irrigation　water　consumption)　and　multiple　water　resource　scenarios　under　climate　change　are　examined　and　discussed　to　provide　more　managerial　insights.　The　results　reveal　that　wheat,　barley,　and　tuber　crops　would　be　more　easily　affected　by　water　resource　availability　and　optimization　goals.　Besides,　recycle　water　would　be　considered　as　an　important　source　for　irrigation　under　scare　water　scenario,　and　gain　the　priority　for　the　economic　purpose.　The　results　also　imply　that　it　is　impossible　to　realize　＂double-win＂　of　environmental　and　economic　goals　simultaneously,　and　decision　makers　should　make　compromises　among　different　strategies.　(C)　2020　Elsevier　Ltd.　All　rights　reserved.