The　comprehensive　control　platform　of　a　simulator　is　the　control　center　of　a　hardware　in　the　loop　simulation　system,　whose　key　technologies　are　timing　precision　and　timing　data　synchronization.　This　paper　achieves　the　precise　timing　using　the　high-precision　timer　under　a　real-time　extension(RTX)　system,　designs　the　driving　program　of　VMIC　card　under　the　RTX　system,　studies　the　data　synchronization　algorithm,　its　flow　chart　and　the　method　for　designing　the　software　of　the　comprehensive　control　platform.　The　study　results　indicate　preliminarily　that　the　hardware　in　the　loop　simulation　system　can　achieve　precise　timing,　does　not　produce　erroneous　frames　or　lose　any　frames,,　ensures　its　synchronization　of　data　transmission　and　thus　is　worth　applying　to　the　development　of　a　missile　weapon　system