Energy　and　water　resources　are　drawing　increasing　attention　in　China　as　indispensable　elements　of　economic　development　and　social　stability.　Energy　and　water　are　interconnected　in　economic　systems.　Although　the　nexus　between　them　has　been　widely　studied,　few　insights　can　be　acquired　by　the　intermediate　transmission　pressures　across　supply　chains.　Combing　betweenness-based　method　and　multi-regional　input-output　(MRIO)　analysis,　we,　in　this　study,　identified　critical　transmission　sectors　and　main　driving　factors　resulting　from　the　usage　structure.　In　details,　we　found　that　Metallurgy　(S14)　in　Shandong,　Henan,　Jiangxi,　Anhui,　Sichuan,　Zhejiang,　Hunan,　and　Jiangsu,　Electricity　and　hot　water　production　and　supply　(S22)　in　Beijing　and　Guizhou,　and　Nonmetal　production　(S13)　in　Henan　are　the　most　critical　transmission　sectors　bearing　energy-water　nexus　pressures,　ranking　at　the　top　100　in　China?s　supply　chain　networks.　Roughly,　the　usage　structure　was　mainly　dominated　by　fixed　capital　formation,　urban　household　consumption　and　trade　export,　and　therefore　should　be　given　priority　to　mitigate　environmental　pressures.　Our　study　provides　a　novel　perspective　of　sector-specific　and　province-typical　policy　recommendations　for　mitigating　energy-water　nexus　pressures　in　China?s　supply　chain　networks.