In　order　to　analyze　the　effect　of　the　smoke　exhaust　system,　a　series　of　experiments　were　conducted　in　a　1:20　scale　model　of　a　cross-type　interchange　subway　station.　Fire　dynamics　simulator　code　was　used　to　evaluate　different　mechanical　smoke　control　strategies　conducted　in　a　full-scale　interchange　subway　station.　The　numerical　results　were　compared　with　experimental　data.　Results　show　that　the　experimental　data　of　the　air　temperature　distribution　in　the　station　platform　were　in　good　agreement　with　the　simulation　results　and　the　research　indicated　that　the　different　smoke　control　system　had　different　influence　on　smoke　confinement　induced　by　the　fire　occurred　in　the　3rd　basement,　which　was　the　platform　of　the　No.10　line　in　Beijing.　In　the　same　smoke　control　strategy,　the　velocity　of　airflow　at　stairs　with　a　full-seal　screen　platform　door　system　in　the　transfer　station　is　higher　than　that　of　platform　the　half-height　screen　platform　door　system.