• 综合
  • 标题
  • 关键词
  • 摘要
  • 学者
  • 期刊-刊名
  • 期刊-ISSN
  • 会议名称
搜索

作者:

Xu Xi (Xu Xi.) | Guan Yu (Guan Yu.) | Li Jianqiang (Li Jianqiang.) (学者:李建强) | Ma Zerui (Ma Zerui.) | Zhang Li (Zhang Li.) | Li Li (Li Li.)

收录:

SCIE PubMed

摘要:

Glaucoma is one of the causes that leads to irreversible vision loss. Automatic glaucoma detection based on fundus images has been widely studied in recent years. However, existing methods mainly depend on a considerable amount of labeled data to train the model, which is a serious constraint for real-world glaucoma detection.In this paper, we introduce a transfer learning technique that leverages the fundus feature learned from similar ophthalmic data to facilitate diagnosing glaucoma. Specifically, a Transfer Induced Attention Network (TIA-Net) for automatic glaucoma detection is proposed, which extracts the discriminative features that fully characterize the glaucoma-related deep patterns under limited supervision. By integrating the channel-wise attention and maximum mean discrepancy, our proposed method can achieve a smooth transition between general and specific features, thus enhancing the feature transferability.To delimit the boundary between general and specific features precisely, we first investigate how many layers should be transferred during training with the source dataset network. Next, we compare our proposed model to previously mentioned methods and analyze their performance. Finally, with the advantages of the model design, we provide a transparent and interpretable transferring visualization by highlighting the key specific features in each fundus image. We evaluate the effectiveness of TIA-Net on two real clinical datasets and achieve an accuracy of 85.7%/76.6%, sensitivity of 84.9%/75.3%, specificity of 86.9%/77.2%, and AUC of 0.929 and 0.835, far better than other state-of-the-art methods.Different from previous studies applied classic CNN models to transfer features from the non-medical dataset, we leverage knowledge from the similar ophthalmic dataset and propose an attention-based deep transfer learning model for the glaucoma diagnosis task. Extensive experiments on two real clinical datasets show that our TIA-Net outperforms other state-of-the-art methods, and meanwhile, it has certain medical value and significance for the early diagnosis of other medical tasks.

关键词:

Attention mechanism Automatic glaucoma diagnosis Deep learning Transfer learning

作者机构:

  • [ 1 ] [Xu Xi]Faculty of Information Technology, Beijing University of Technology, Beijing, China
  • [ 2 ] [Guan Yu]Faculty of Information Technology, Beijing University of Technology, Beijing, China
  • [ 3 ] [Li Jianqiang]Faculty of Information Technology, Beijing University of Technology, Beijing, China. bjut_lijianqiang@163.com
  • [ 4 ] [Ma Zerui]Faculty of Information Technology, Beijing University of Technology, Beijing, China
  • [ 5 ] [Zhang Li]Beijing Tongren Hospital, Capital Medical University, Beijing, China
  • [ 6 ] [Li Li]Beijing Children's Hospital, Capital Medical University, Beijing, China

通讯作者信息:

电子邮件地址:

查看成果更多字段

相关关键词:

来源 :

Biomedical engineering online

ISSN: 1475-925X

年份: 2021

期: 1

卷: 20

页码: 39

3 . 9 0 0

JCR@2022

ESI学科: MOLECULAR BIOLOGY & GENETICS;

ESI高被引阀值:9

被引次数:

WoS核心集被引频次: 0

SCOPUS被引频次: 28

ESI高被引论文在榜: 0 展开所有

万方被引频次:

中文被引频次:

近30日浏览量: 2

归属院系:

在线人数/总访问数:469/2899885
地址:北京工业大学图书馆(北京市朝阳区平乐园100号 邮编:100124) 联系我们:010-67392185
版权所有:北京工业大学图书馆 站点建设与维护:北京爱琴海乐之技术有限公司