In　recent　years,　the　safety　of　the　bridge　structure　has　been　challenge　due　to　the　vehicle　collision　on　the　pier,　and　the　accident　of　vehicle　collision　has　caused　a　lot　of　economic　losses.　With　the　development　of　precast　bridge　structure,　the　dynamic　performance　of　precast　segment　pier　has　attracted　extensive　attention.　The　dynamic　responses　and　failure　modes　of　bridge　precast　segment　piers　under　vehicle　collision　were　investigated　in　this　work.　Firstly,　the　numerical　model　of　precast　segment　column　under　impact　loads　was　established,　and　its　reliability　was　verified.　Secondly,　the　numerical　models　of　bridge　precast　segment　pier　and　cast-in-place　pier　were　established　to　analyze　differences　of　dynamic　performance　under　vehicle　collision.　The　failure　modes,　impact　force　and　displacement　of　bridge　precast　segment　pier　and　cast-in-place　pier　were　studied　in　detail.　Finally,　the　factors　of　impact　velocity,　concrete　strength,　pre-stressing　level　and　number　of　segments　were　considered　respectively.　The　numerical　results　show　that　the　damage　of　precast　segment　pier　is　smaller　than　that　of　cast-in-place　pier　under　vehicle　collision,　and　the　peak　impact　force　of　precast　segment　pier　is　slightly　lower　than　that　of　cast-in-place　pier.　The　prestressing　level　and　number　of　segments　have　no　obvious　effect　on　impact　force　of　precast　segment　pier　under　vehicle　collision.　The　relative　displacements　between　precast　segments　under　vehicle　collision　need　to　be　taken　into　account　in　design.