Precious　metal　catalysts　with　superior　low-temperature　activity　and　excellent　thermal　stability　are　highly　needed　in　environmental　catalysis　field.　In　this　work,　a　novel　two-step　incipient　wetness　impregnation　(T-IWI)　method　was　developed　for　the　fabrication　of　a　unique　and　highly　stable　CeO2/Al2O3　support　(CA-T).　Pd　anchored　on　CA-T　exhibited　a　much　higher　low-temperature　catalytic　activity　and　superior　thermal　stability　in　carbon　monoxide　(CO)　and　hydrocarbon　(HC)　oxidations,　compared　to　Pd　anchored　on　conventional　CeO2/Al2O3　(CA),　which　was　prepared　by　a　one-step　IWI　method.　After　aging　treatment　at　800　°C,　the　CO　oxidation　rate　on　Pd/CA-T　(1.69　mmol/(gPd　s))　at　120　°C　was　4.1　and　84.5　times　of　those　on　Pd/CA　(0.41　mmol/(gPd　s))　and　Pd/Al2O3　(0.02　mmol/(gPd　s)),　respectively.　It　was　revealed　that　the　CA-T　support　with　well-controlled　small　CeO2　particles　(ca.　12　nm)　possessed　abundant　defects　for　Pd　anchoring,　which　created　rich　Pd-CeO2　interfaces　with　strengthened　interaction　between　Pd　and　CeO2　where　oxygen　could　be　efficiently　activated.　This　resulted　in　the　significantly　improved　oxidation　activity　and　thermal　stability　of　Pd/CA-T　catalysts.　The　T-IWI　method　developed　herein　can　be　applied　as　a　universal　approach　to　prepare　highly　stable　metal　oxide-alumina-based　supports,　which　have　broad　application　in　environmental　catalyst　design,　especially　for　automobile　exhaust　aftertreatment.