1-Ethyl-3-methylimidazolium　bis[(trifluoromethyl)sulfonyl]imide　([EMIM][Tf2N])　ionic　liquid　as　a　novel　absorbent　has　excellent　performance　in　BTX　absorption.　However,　compared　with　the　traditional　method　using　triethylene　glycol　(TEG),　the　sustainability　of　the　former　is　unknown.　Thus,　to　bridge　the　gap　and　give　a　comprehensive　evaluation　of　its　industrialization　potential,　a　methodology-integrated　energetic,　economic,　and　environmental　assessment　was　employed.　The　assessment　results　show　that　the　heating　and　cooling　energy　consumptions　of　the　TEG　process　are　1.08　and　0.74　times　higher　than　those　of　the　[EMIM][Tf2N]　process,　respectively.　But　through　heat　integration,　5%　hot　and　3.4%　cold　utilities　can　be　saved　for　the　[EMIM][Tf2N]　process.　In　terms　of　economic　performance,　the　total　annual　costs　for　TEG　and　[EMIM][Tf2N]　processes　are　0.6111　and　0.4841　M$/year,　respectively,　and　the　latter　is　26.3%　lower　than　the　former.　As　for　the　environmental　assessment,　the　results　indicated　that　compared　with　the　TEG　scenario,　the　[EMIM][Tf2N]　scenario　without　absorbent　recovery　presented　higher　environmental　burdens　in　all　categories,　and　the　largest　difference　lies　in　acidification,　for　which　the　latter　is　42　times　that　of　the　former.　However,　when　considering　the　absorbent　recovery,　the　results　are　contradictory.　Thus,　the　comprehensive　assessment　methodology　proved　that　the　[EMIM][Tf2N]-based　BTX　absorption　process　is　sustainable　and　can　be　a　potential　industrialization　technology.　©　2021　American　Chemical　Society.