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Author:

Liu, Sida (Liu, Sida.) | Chen, Jimin (Chen, Jimin.) | Chen, Tao (Chen, Tao.) | Zeng, Yong (Zeng, Yong.)

Indexed by:

EI Scopus SCIE

Abstract:

The introduction of 3D printing into the manufacturing of ceramic components offers new possibilities to fabricate porous bioceramic scaffold with biomimetic morphology, customized-designed shape and suitable mechanical property for bone tissue engineering. However, most of 3D printed porous ceramic scaffolds are prepared from the array of unit cells, which do not exploit the whole potential of additive manufacturing. In this paper, a novel biomimetic porous beta-tricalcium phosphate (13-TCP) scaffolds with trabecular-like morphology were obtained based on three dimension (3D) Voronoi tessellation method and generated design. This bionic pore structure is fabricated via photopolymer-based digital light processing (DLP) 3D printing technique, a suitable 30 wt% 13-TCP ceramic slurry with the addition of adjuvants was prepared. After optimized debindingsintering process according the TG-DSC analysis, the 13-TCP scaffolds showed fully interconnected trabecular-like pore structure with tailorable pore size (360 ?m?1200 ?m) and porosity (45%?75%) and compact microstructure. Combining compressive tests and finite element analysis (FEA), the relationship between inputting parameters, pore structure and compressive strength is investigated. Thus, the mechanical strength of the trabecular-like 13-TCP scaffolds could be predicted and tuned in the initial generated design stage. In addition, the shrinkage ratio and XRD pattern are also detected. The method proposed in this study may provide an efficient bionic design intended for tissue engineering applications.

Keyword:

Voronoi tessellation Bio-inspired design Bone tissue engineering Beta-tricalcium phosphate 3D printing

Author Community:

  • [ 1 ] [Liu, Sida]Beijing Univ Technol, Beijing Engn Res Ctr 3D Printing Digital Med Hlth, Beijing 100124, Peoples R China
  • [ 2 ] [Chen, Jimin]Beijing Univ Technol, Beijing Engn Res Ctr 3D Printing Digital Med Hlth, Beijing 100124, Peoples R China
  • [ 3 ] [Chen, Tao]Beijing Univ Technol, Beijing Engn Res Ctr 3D Printing Digital Med Hlth, Beijing 100124, Peoples R China
  • [ 4 ] [Zeng, Yong]Beijing Univ Technol, Beijing Engn Res Ctr 3D Printing Digital Med Hlth, Beijing 100124, Peoples R China
  • [ 5 ] [Liu, Sida]Beijing Univ Technol, Beijing Int Sci & Technol Cooperat Base 3D Printi, Beijing 100124, Peoples R China
  • [ 6 ] [Chen, Jimin]Beijing Univ Technol, Beijing Int Sci & Technol Cooperat Base 3D Printi, Beijing 100124, Peoples R China
  • [ 7 ] [Chen, Tao]Beijing Univ Technol, Beijing Int Sci & Technol Cooperat Base 3D Printi, Beijing 100124, Peoples R China
  • [ 8 ] [Zeng, Yong]Beijing Univ Technol, Beijing Int Sci & Technol Cooperat Base 3D Printi, Beijing 100124, Peoples R China
  • [ 9 ] [Liu, Sida]Beijing Univ Technol, Key Lab Trans Scale Laser Mfg Technol, Minist Educ, Beijing 100124, Peoples R China
  • [ 10 ] [Chen, Jimin]Beijing Univ Technol, Key Lab Trans Scale Laser Mfg Technol, Minist Educ, Beijing 100124, Peoples R China
  • [ 11 ] [Chen, Tao]Beijing Univ Technol, Key Lab Trans Scale Laser Mfg Technol, Minist Educ, Beijing 100124, Peoples R China
  • [ 12 ] [Zeng, Yong]Beijing Univ Technol, Key Lab Trans Scale Laser Mfg Technol, Minist Educ, Beijing 100124, Peoples R China
  • [ 13 ] [Liu, Sida]Beijing Univ Technol, Fac Mat & Mfg, Beijing 100124, Peoples R China
  • [ 14 ] [Chen, Jimin]Beijing Univ Technol, Fac Mat & Mfg, Beijing 100124, Peoples R China
  • [ 15 ] [Chen, Tao]Beijing Univ Technol, Fac Mat & Mfg, Beijing 100124, Peoples R China
  • [ 16 ] [Zeng, Yong]Beijing Univ Technol, Fac Mat & Mfg, Beijing 100124, Peoples R China
  • [ 17 ] [Liu, Sida]GRIMED Med Beijing Co Ltd, Beijing 102200, Peoples R China

Reprint Author's Address:

  • [Chen, Jimin]Beijing Univ Technol, Beijing Engn Res Ctr 3D Printing Digital Med Hlth, Beijing 100124, Peoples R China

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Source :

CERAMICS INTERNATIONAL

ISSN: 0272-8842

Year: 2021

Issue: 9

Volume: 47

Page: 13187-13198

5 . 2 0 0

JCR@2022

ESI Discipline: MATERIALS SCIENCE;

ESI HC Threshold:116

JCR Journal Grade:1

Cited Count:

WoS CC Cited Count: 29

SCOPUS Cited Count: 43

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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