In　order　to　study　the　earthquake　response　characteristics　and　disaster　mechanism　of　integrated　subway　station　structure　of　urban　rail　transit,　a　large-scale　three-dimensional　finite　element　numerical　model　of　static-dynamic　coupling　was　established　by　ABAQUS　finite　element　software　based　on　the　plastic　damage　theory　of　concrete.　The　earthquake　damage　evolution　process,　failure　mechanism　and　spatial　effect　of　the　integrated　subway　station　structure　of　urban　rail　transit　hub　were　analyzed　and　discussed.　The　results　show　that　integrated　structure　of　urban　rail　transit　hub　has　the　characteristics　of　subway　underground　station　structure　and　above-ground　structure,　and　the　dynamic　characteristics　and　response　of　the　original　single　station　structure　change.　The　horizontal　displacement　of　integrated　subway　station　structure　decreases　gradually　with　the　increase　of　buried　depth　of　station　structure,　and　the　relative　horizontal　displacement　between　floors　increases　gradually　with　the　increase　of　buried　depth　of　station　structure.　The　plastic　deformation　occurs　in　the　direction　of　cross　section　and　the　vertical　direction　of　station　structure,　which　shows　the　phenomenon　of　plastic　accumulation.　The　joint　of　floor　slab　and　wall　column　is　the　most　disadvantageous　position.　The　damage　of　bottom　middle　column　and　side　wall　bottom　is　the　most　serious,　which　is　the　weak　part　of　the　whole　integrated　subway　station　structure.　Therefore,　the　seismic　measures　of　the　structural　members　at　the　bottom　of　the　station　should　be　strengthened.　The　integrated　subway　station　structure　of　urban　rail　transit　hub　shows　significant　spatial　effect.　The　displacement　response　and　internal　force　response　of　different　areas　of　subway　station　are　significantly　different.　The　horizontal　displacement　between　floors　of　the　integrated　area　is　about　5%　of　that　of　the　non-integrated　area,　while　the　maximum　value　of　shear　force　at　the　end　of　the　column　increases　by　200%.　©　2021,　Central　South　University　Press.　All　right　reserved.