The　multiple　pulses　propagation　through　rock　mass　with　micro-defect　and　macro-joint　was　investigated.　The　traditional　split　three　characteristic　lines　method　was　modified　by　considering　the　different　mechanical　behaviors　of　macro-joint　under　multiple　pulses,　which　is　characterized　by　the　cyclic　loading　Barton-Bandis　(BB)　model.　The　effects　of　time　interval,　frequency　and　amplitude　of　multiple　pulses　on　the　transmission　coefficient,　effective　velocity　and　energy　transmission　coefficient　were　investigated.　The　results　show　that　the　effects　of　time　interval　on　the　transmission　coefficient　and　effective　velocity　of　the　head　pulse　can　be　neglected,　while　the　effect　on　energy　transmission　coefficient　of　the　head　pulse　cannot　be　neglected,　and　the　energy　transmission　coefficient　of　the　head　pulse　increases　as　the　increase　of　the　time　interval.　On　the　other　hand,　the　transmission　coefficient,　effective　velocity　and　energy　transmission　coefficient　of　the　subsequent　pulses　all　decreases　as　the　increase　of　the　time　interval.　In　addition,　the　effective　velocity　of　head　pulse　is　significantly　affected　by　frequency,　while　that　of　subsequent　pulses　is　less　affected　by　frequency.　The　transmission　coefficient　and　energy　transmission　coefficient　of　head　pulse　and　subsequent　pulses　are　significantly　affected　by　frequency.　The　transmission　coefficient,　the　effective　velocity　and　the　energy　transmission　coefficient　of　head　pulse　are　significantly　affected　by　amplitude,　while　those　of　subsequent　pulses　are　less　affected　by　amplitude.　©　2021　Elsevier　Ltd