In　this　study,　a　new　type　of　self-lubricating　nanoparticle　diamond　grinding　wheel　with　MoS2　and　TiO2　nanoparticles　as　filling　materials　was　proposed.　According　to　the　macro　parameters　(grinding　force)　and　micro　parameters　(surface　roughness,　surface　morphology,　grinding　wheel　wear),　the　lubricated　characteristic　on　tool　and　workpiece　surface　with　various　concentrations　of　nanoparticles　was　studied.　The　research　indicated　that　the　composite　nanoparticles　can　effectively　improve　the　lubricated　characteristic　of　the　tool.　The　nanoparticles　released　from　the　grinding　wheel　can　participate　in　lubrication　and　decrease　the　adhesion　of　abrasive　grains　to　the　workpiece　surface,　so　as　to　enhance　the　surface　quality　of　the　workpiece.　Moreover,　there　is　a　suitable　addition　range　of　composite　nanoparticles　in　the　grinding　wheel.　Adding　too　little　or　exceeding　this　range　will　weaken　the　friction　reduction　performance　of　the　nanoparticles.　It　had　the　best　lubrication　performance　and　surface　quality　of　the　workpiece　at　a　nanoparticle　volume　concentration　of　8%.