BACKGROUND　Although　LVADs　are　confirmed　to　have　strong　effects　on　aortic　hemodynamics,　the　precise　mechanisms　of　the　helical　flow　component　of　LVAD　outflow　are　still　unclear.　MATERIAL　AND　METHODS　To　clarify　these　effects,　3　cases　-　normal　case,　flat　flow　case,　and　realistic　flow　case　-　were　designed　and　studied　by　using　the　CFD　approach.　The　normal　case　denoted　the　normal　aorta　without　LVAD　support,　and　the　flat　flow　case　represented　the　aorta　with　the　outflow　cannula.　Similarly,　the　realistic　flow　case　included　the　aortic　model,　the　model　of　outflow　cannula,　and　the　model　of　LVAD.　The　velocity　vector,　blood　streamline,　distribution　of　wall　shear　stress　(WSS),　and　the　local　normalized　helicity　(LNH)　were　calculated.　RESULTS　The　results　showed　that　the　helical　component　of　LVAD　outflow　significantly　improved　the　aortic　hemodynamics.　Compared　with　the　flat　flow　case,　the　helical　flow　eliminated　the　vortex　near　the　outer　wall　of　the　aorta　and　improved　the　blood　flow　transport　(normal　case　0.1　m/s　vs.　flat　flow　case　0.14　m/s　vs.　realistic　flow　case　0.30　m/s)　at　the　descending　aorta.　Moreover,　the　helical　flow　was　confirmed　to　even　the　distribution　of　WSS,　reduce　the　peak　value　of　WSS　(normal　case　0.92　Pa　vs.　flat　flow　case　7.39　Pa　vs.　realistic　flow　case　5.2Pa),　and　maintain　a　more　orderly　WSS　direction.　CONCLUSIONS　The　helical　flow　component　of　LVAD　outflow　has　significant　advantages　for　improving　aortic　hemodynamic　stability.　Our　study　provides　novel　insights　into　LVAD　optimization.