In　order　to　objectively　elucidate　the　state　of　the　membrane　after　long-term　operation,　the　performance　of　a　full-scale　microfiltration-reverse　osmosis　(MF-RO)　integrated　membrane　system　with　production　capacity　of　20,000　m3/d　for　wastewater　reclamation　was　evaluated　by　collecting　10　years　performance　data.　The　foulants　on　1　MF　membrane　and　12　RO　membranes　along　the　feed　channel　also　were　analyzed　by　membrane　autopsy.　The　results　indicate　that　the　water　quality　of　the　system　can　still　meet　the　customer　requirements　while　the　mechanical　and　desalting　properties　of　the　membranes　were　close　to　the　abandoned　standards.　In　terms　of　foulants　distribution,　the　MF　membrane　surface　was　covered　by　a　thick　cake　layer　and　the　leading　RO　membrane　suffered　the　highest　fouling　load.　The　predominate　organic　foulants　on　the　membrane　surface　were　protein　and　polysaccharide,　and　the　main　inorganic　foulants　were　Fe　and　Ca,　and　their　distribution　showed　two　different　trends　along　the　feed　channel.　Regarding　bio-foulants,　the　compositions　of　bacterial　colonies　on　12　RO　membranes　were　basically　the　same,　but　the　relative　abundance　of　the　dominant　bacteria　was　different　and　the　microbial　diversity　increased　gradually　from　the　leading　element　to　the　terminal　one　in　both　the　two　stages.　©　Content　from　this　work　may　be　used　under　the　terms　of　the　Creative　Commons　Attribution　3.0　licence.