H.264/AVC　is　the　latest　video　coding　standard　with　high　compression　efficiency.　Due　to　its　time-consuming　in　coding,　it　cannot　meet　the　real-time　application　requirements.　In　this　paper,　an　efficient　algorithm　was　proposed　based　on　2D-Histogram　according　to　the　feature　of　Intra-frame　prediction.　In　this　algorithm,　each　macroblock　is　predicted　before　coding,　and　one　of　the　two　prediction　modes　is　selected.　As　a　result　of　this　processing,　coding　time　has　been　reduced　dramatically.　Experimental　results　show　that　the　coding　time　of　proposed　algorithm　is　16.26%　less　than　that　of　H.264/AVC,　at　the　expense　of　little　quality　degradation.