To　solve　the　ventilation　problems　of　Jinchuan　Group　Ltd,　mine　ventilation　simulation　system　is　constructed　and　developed　by　using　ventilation　network　theory,　graph　theory,　set　theory.　The　functions　and　optimal　adjustment　mathematical　model　of　Mine　Ventilation　Simulation　System　(MVSS)　are　discussed,　and　MVSS　is　used　to　simulate　the　influences　of　the　increase　or　decrease　of　roadways　on　the　surrounding　other　roadways　and　to　simulate　the　influences　of　the　backouts　or　installations　of　fan　stations　on　the　surrounding　ventilation　system.　The　method　of　determining　optimization　and　reconstruction　schemes　by　using　MVSS　is　illustrated　with　the　example　of　1　150　level　of　Jinchuan　mine,　which　provides　a　scientific　tool　for　the　analysis　of　ventilation　system　actuality,　ventilation　network　optimums　and　ventilation　designs.