Recently　CAD/CAM　technology　has　been　gradually　used　in　the　field　of　laser　processing.　The　excimer　laser　micro-processing　system　just　identified　G　instruction　before　CAD/CAM　interface　was　designed.　However　the　course　of　designing　a　part　with　G　instruction　for　users　is　too　hard.　The　efficiency　is　low　and　probability　of　making　errors　is　high.　By　secondary　development　technology　of　AutoCAD　with　Visual　Basic,　an　application　was　developed　to　pick-up　each　entity＇s　information　in　graph　and　convert　them　to　each　entity＇s　processing　parameters.　Also　an　additional　function　was　added　into　former　controlling　software　to　identify　these　processing　parameters　of　each　entity　and　realize　continue　processing　of　graphic.　Based　on　the　above　CAD/CAM　interface,　Users　can　design　a　part　in　AutoCAD　instead　of　using　G　instruction.　The　period　of　designing　a　part　is　sharply　shortened.　This　new　way　of　design　greatly　guarantees　the　processing　parameters　of　the　part　is　right　and　exclusive.　The　processing　of　complex　novel　bio-chip　has　been　realized　by　this　new　function.