Multiple　square　loops-string　dome　is　a　newly　suspen-dome　structure,　and　cable　failure　shows　significant　effect　on　multiple　square　loops-string　dome　structures.　This　paper　used　the　Fuzhou　Strait　Olympic　Center　Gymnasium　as　the　research　background　to　study　the　effect　of　cable　on　the　vertical　stiffness　of　the　roof,　the　internal　forces　of　the　roof　and　the　ultimate　bearing　capacity,　and　safety　capability　evaluation　of　the　cable　failure　roof　was　carried　out.　The　analysis　results　show　that　the　vertical　deformation　of　the　roof　can　be　reduced　after　cable　failure.　Among　them,　the　failure　of　the　outer　loop　cable　causes　the　maximum　vertical　deformation.　However,　various　vertical　deformation　distributions　subjected　to　different　cable　failure　are　generated.　The　failure　of　either　the　outer　loop　or　string　cable　can　increase　the　tension　force　of　the　adjacent　cable　significantly.　The　interaction　between　the　outer　loop　cable　and　string　cable　is　greater　than　the　mutual　influence　between　the　other　loop　cables;　Ultimate　bearing　capacity　of　the　roof　can　be　reduced　when　cable　failure　occurs,　which　reaches　the　minimum　value　when　the　outer　loop　cable　fails.　It　should　be　noted　that　＇Only　one　side　string　cable　failure＇　causes　more　serious　deflection　and　less　ultimate　bearing　capacity　when　compared　with＇two　side　string　cable　failure＇.　In　all,　failure　of　the　outer　loop　cable　is　the　most　serious　case,　which　causes　that　vertical　deflection　increases　by　134%,　the　cable　tension　force　of　adjacent　cable　increases　by　11.7%,　and　the　ultimate　bearing　capacity　reduces　by　35%.　However,　the　residual　roof　structure　is　still　in　a　safe　state.　©　2020,　Editorial　Department　of　Journal　of　Hunan　University.　All　right　reserved.