The　cryptomelane-type　octahedral　molecular　sieve　(OMS-2)　exhibits　excellent　catalytic　activity　for　the　oxidation　of　volatile　organic　compounds　(VOCs)　due　to　its　unique　structure,　and　single-atom　catalysts　(SACs)　have　recently　attracted　much　attention　in　heterogeneous　catalysis.　Herein,　we　adopted　the　hydrothermal　redox　reaction　of　KMnO4　and　HCl　aqueous　solution　at　120　degrees　C　for　12　h　to　first　synthesize　the　nanotubular　OMS-2　support　and　used　the　vitamin　C　and　NaBH4　reduction　methods　to　prepare　the　OMS-2-supported　single-atom　Pt　and　Pt-NP　catalysts　for　benzene　oxidation,　respectively.　It　was　found　that　the　OMS-2-supported　single-atom　Pt　catalyst　with　a　Pt　loading　of　0.0383　wt　%　(0.0383Pt(1)/OMS-2)　exhibited　the　best　catalytic　performance　for　benzene　oxidation　(a　90%　benzene　conversion　was　achieved　at　189　degrees　C　and　20　000　mL　g(-1)　h(-1)　(space　velocity)),　which　was　associated　with　its　high　surface　oxygen　vacancy　density,　good　lowtemperature　reducibility,　and　strong　benzene　adsorption　ability.　It　was　also　shown　that　benzene　could　be　dissociated　more　readily　over　the　supported　single-atom　Pt-1　catalyst　than　over　the　supported　Pt-NP　catalyst,　and　the　phenolates　or　benzoquinone　as　well　as　methyl　groups,　lipid,　and　vinyl　species　were　the　main　intermediates　in　the　oxidation　of　benzene　over　0.0383Pt(1)/OMS-2.　The　results　of　this　study　are　useful　in　developing　the　high-performance　single-atom　catalysts　that　can　be　applied　for　the　oxidative　removal　of　VOCs.