Y　At　present,　the　studies　on　magnetocaloric　properties　are　mainly　based　on　polycrystalline　materials,　which　is　not　enough　to　reveal　and　understand　the　origin　of　their　magnetocaloric　effect.　In　addition,　finding　new　room　temperature　magnetocaloric　materials　is　crucial　to　the　development　and　application　for　room　temperature　magnetic　refrigeration.　Here,　we　report　the　magnetic　transitions,　magnetic　anisotropy,　and　magnetocaloric　properties　of　single-crystal　Mn5Ge3　and　Mn5Ge3/Mn3.5Fe1.5Ge3　heterostructures　with　six　(100)　surfaces　and　the　[001]　growth　direction　prepared　using　the　Sn　flux　method.　Mn5Ge3　(Mn3.5Fe1.5Ge3)　undergoes　a　sharp　paramagnetic-collinear　ferromagnetic　transition　at　299　(332)　K　and　weak　collinear-noncollinear　ferromagnetic　transition　at　65　(35)　K.　Owing　to　the　distinct　spin　arrangements　and　magnetic　moments　of　Mn5Ge3　and　Mn3.5Fe1.5Ge3,　the　magnetic　anisotropy　of　the　single　crystal　is　stronger　than　that　of　the　heterostructure　below　299　K.　Moreover,　a　large　anisotropic　magnetocaloric　effect,　wide　operating　temperature　range,　and　large　refrigeration　capacity　near　room　temperature　are　obtained　in　these　two　materials,　especially　the　magnetocaloric　effect　of　the　heterostructure　presents　a　tablelike　shape　due　to　the　adjacent　paramagnetic-collinear　ferromagnetic　transitions　of　Mn5Ge3　and　Mn3.5Fe1.5Ge3.　Under　0-3　T,　the　maximum　magnetic　entropy　change,　operating　temperature　range,　and　refrigeration　capacity　of　the　single　crystal　(heterostructure)　are　5.19　(2.96)　J　kg(-1)　K-1,　43　(57)　K,　and　223　(169)　J　kg(-1)　when　H//c,　respectively.　These　features　make　them　candidates　for　room　temperature　magnetic　refrigeration.