Research　on　the　design,　synthesis,　and　application　of　metal　organic　frameworks　(MOFs)　based　on　flexible　ligands　has　attracted　significant　attention　in　recent　years　owing　to　their　superior　performance　in　applications　such　as　gas　adsorption　and　molecular　separation.　In　this　work,　two　acs-type　MOFs　and　an　Nbo-type　MOF　derived　from　three　different　flexible　diisophthalate　ligands　were　solvothermally　prepared　and　structurally　characterized　by　single　crystal　X-ray　diffraction,　powder　X-ray　diffraction,　and　thermogravimetric　analysis.　Analyses　of　the　data　revealed　that　the　topologies　of　the　MOFs　were　correlated　to　the　dihedral　angle　between　the　phenyl　rings　in　the　ligands.