Green　manufacturing　is　a　growing　trend,　and　an　effective　layout　design　method　for　production　lines　can　reduce　resource　wastage　in　processing.　This　study　focuses　on　existing　problems　such　as　low　equipment　utilization,　long　standby　time,　and　low　logistics　efficiency　in　a　mixed-flow　parallel　production　line.　To　reduce　the　energy　consumption,　a　novel　method　considering　an　independent　buffer　configuration　and　idle　energy　consumption　analysis　is　proposed　for　this　production　line＇s　layout　design.　A　logistics　intensity　model　and　a　machine　tool　availability　model　are　established　to　investigate　the　influences　of　independent　buffer　area　configuration　on　the　logistics　intensity　and　machine　tool　availability.　To　solve　the　coupling　problem　between　machine　tools　in　such　production　lines,　a　decoupling　strategy　for　the　relationship　between　machine　tool　processing　rates　is　explored.　An　energy　consumption　model　for　the　machine　tools,　based　on　an　optimized　configuration　of　independent　buffers,　is　proposed.　This　model　can　effectively　reduce　the　idle　energy　consumption　of　the　machine　tools　while　designing　the　workshop　layout.　Subsequently,　considering　the　problems　encountered　in　workshop　production,　a　comprehensive　optimization　model　for　the　mixed-flow　production　line　is　developed.　To　verify　the　effectiveness　of　the　mathematical　model,　it　is　applied　to　an　aviation　cabin　production　line.　The　results　indicate　that　it　can　effectively　solve　the　layout　problem　of　mixed-flow　parallel　production　lines　and　reduce　the　idle　energy　consumption　of　machine　tools　during　production.　The　proposed　buffer　configuration　and　layout　design　method　can　serve　as　a　theoretical　and　practical　reference　for　the　layout　design　of　mixed-flow　parallel　production　lines.