Engineering　the　local　coordination　environment　in　atomically　dispersed　catalyst　has　proven　to　be　a　prospective　route　to　boost　catalyst　performance　for　hydrogen　evolution　reaction　(HER).　Herein,　we　present　the　utilization　of　local　lattice　distortion　of　TiO2　support　to　regulate　the　local　coordination　environment　and　electronic　structures　of　atomically　dispersed　Pt　catalysts,　resulting　in　the　enhanced　performance　toward　HER.　Spectral　analysis　uncovers　an　elongated　Pt-O　bond　length,　lower　Pt-O　co-ordination　numbers,　as　well　as　less　electron　holes　residing　in　Pt　5d　orbitals　for　Pt　species　on　distorted　TiO2.　Density　functional　theory　(DFT)　calculation　reveal　that　the　variation　might　weaken　the　hydrogen　adsorption　on　Pt　sites　and　cause　the　optimized　Delta　G　value　of　H*.　As　a　result,　the　atomically　dispersed　Pt　catalyst　displays　superior　HER　mass　activity　(62.34　A　mg(-1)　Pt)　and　the　highest　turnover　frequency　(TOF)　(56.1　H-2.s(-1))　at　the　50　mV　overpotential　in　an　acid　media　that　are　18.7　and　5.56　times　higher　than　commercial　Pt/C.　The　work　should　create　a　new　avenue　in　manipulating　the　local　coordination　environment　of　catalysts　via　the　lattice　distortion　of　the　support,　and　in　pursuing　desired　catalytic　performance.　(C)　2021　Elsevier　Ltd.　All　rights　reserved.