Safety　management　in　hoisting　is　the　key　issue　to　determine　the　development　of　prefabricated　building　construction.　However,　the　security　management　in　the　hoisting　stage　lacks　a　truly　effective　method　of　information　physical　fusion,　and　the　safety　risk　analysis　of　hoisting　does　not　consider　the　interaction　of　risk　factors.　In　this　paper,　a　hoisting　safety　risk　management　framework　based　on　digital　twin　(DT)　is　presented.　The　digital　twin　hoisting　safety　risk　coupling　model　is　built.　The　proposed　model　integrates　the　Internet　of　Things　(IoT),　Building　Information　Modeling　(BIM),　and　a　security　risk　analysis　method　combining　the　Apriori　algorithm　and　complex　network.　The　real-time　perception　and　virtual-real　interaction　of　multi-source　information　in　the　hoisting　process　are　realized,　the　association　rules　and　coupling　relationship　among　hoisting　safety　risk　factors　are　mined,　and　the　time-varying　data　information　is　visualized.　Demonstration　in　the　construction　of　a　large-scale　prefabricated　building　shows　that　with　the　proposed　framework,　it　is　possible　to　complete　the　information　fusion　between　the　hoisting　site　and　the　virtual　model　and　realize　the　visual　management.　The　correlative　relationship　among　hoisting　construction　safety　risk　factors　is　analyzed,　and　the　key　control　factors　are　found.　Moreover,　the　efficiency　of　information　integration　and　sharing　is　improved,　the　gap　of　coupling　analysis　of　security　risk　factors　is　filled,　and　effective　security　management　and　decision-making　are　achieved　with　the　proposed　approach.