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作者:

Yang, Shuai (Yang, Shuai.) | Luo, Yunjing (Luo, Yunjing.) | Mu, Lei (Mu, Lei.) | Yang, Youyou (Yang, Youyou.) | Yang, Yongtan (Yang, Yongtan.)

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摘要:

An liquid chromatography-tandem mass spectrometry method coupled with a stable isotope dilution assay was established for the simultaneous detection of 17 mycotoxins and their derivatives (aflatoxins B-1, B-2, G(1), G(2), M-1, and M-2; fumonisins B-1 and B-2; ochratoxin A; zearalenone; zearalanone; alpha-zearalanol; alpha-zearalenol; T-2 toxin; deoxynivalenol; deepoxy-deoxynivalenol; and sterigmatocystin) in milk and dairy products. The mycotoxins were extracted with acidified acetonitrile and the lipids were removed using a Captiva EMR-lipid column. The average recoveries of the target compounds from samples spiked at three different concentrations were 67-102%, and the relative standard deviations of the peak areas were less than 10%. Limits of quantification (S/N = 10) of 0.004-1.25 mu g/kg were achieved, which are significantly lower than the maximum levels allowed in various countries and regions for each regulated mycotoxin. Milk and yogurt products from local markets and e-commercial platforms were analyzed using the optimized method. The screening showed that aflatoxin M-1, deoxynivalenol, fumonisins B-1 and B-2, and zearalenone could be found in milk and yogurt products, especially those products also containing grains or jujube ingredients, indicating that there is a risk of mycotoxins in dairy products.

关键词:

risk assessment dairy multimycotoxins isotope dilution

作者机构:

  • [ 1 ] [Yang, Shuai]China Oil & Foodstuffs Corp COFCO Nutr & Hlth Res, 4 Rd,Future Sci & Technol Pk South, Beijing 102209, Peoples R China
  • [ 2 ] [Mu, Lei]China Oil & Foodstuffs Corp COFCO Nutr & Hlth Res, 4 Rd,Future Sci & Technol Pk South, Beijing 102209, Peoples R China
  • [ 3 ] [Yang, Youyou]China Oil & Foodstuffs Corp COFCO Nutr & Hlth Res, 4 Rd,Future Sci & Technol Pk South, Beijing 102209, Peoples R China
  • [ 4 ] [Yang, Shuai]Beijing Key Lab Nutr Hlth & Food Safety, Beijing, Peoples R China
  • [ 5 ] [Mu, Lei]Beijing Key Lab Nutr Hlth & Food Safety, Beijing, Peoples R China
  • [ 6 ] [Yang, Youyou]Beijing Key Lab Nutr Hlth & Food Safety, Beijing, Peoples R China
  • [ 7 ] [Yang, Youyou]Inst Anim Sci CAAS, Beijing, Peoples R China
  • [ 8 ] [Yang, Shuai]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China
  • [ 9 ] [Luo, Yunjing]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China
  • [ 10 ] [Yang, Yongtan]Acad State Adm Grain, Beijing, Peoples R China

通讯作者信息:

  • [Yang, Youyou]China Oil & Foodstuffs Corp COFCO Nutr & Hlth Res, 4 Rd,Future Sci & Technol Pk South, Beijing 102209, Peoples R China;;[Yang, Yongtan]Acad Natl Food & Strateg Reserves Adm, Beijing 100037, Peoples R China

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来源 :

JOURNAL OF SEPARATION SCIENCE

ISSN: 1615-9306

年份: 2020

期: 4

卷: 44

3 . 1 0 0

JCR@2022

ESI学科: CHEMISTRY;

ESI高被引阀值:139

被引次数:

WoS核心集被引频次: 15

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