As　a　supporting　facility,　expressway　service　area　is　of　great　significance　to　the　rapid　development　of　expressway.　In　order　to　evaluate　the　effectiveness　of　traffic　signs　and　markings　of　expressway　service　area　from　human　factor,　this　paper　adopts　driving　simulator　technology.　The　traffic　signs　and　markings　of　Shangdian　expressway　service　area　of　Beijing　Xingyan　expressway　was　the　research　object　and　the　immersive　3D　driving　simulation　scenario　was　built.　Then,　the　driving　simulation　experiment　was　designed　based　on　the　way-finding　theory.　31　subjects　were　recruited　to　participate　in　the　experiment.　Finally,　based　on　driving　behavior　data,　the　effectiveness　of　traffic　signs　and　markings　in　each　zone　was　evaluated.　The　result　shows　that　longitudinal　and　lateral　deceleration　marking,　sign　and　uncolored　pavement　word,　colored　pavement　word　should　be　set　in　the　entrance　zone,　diverging　area　for　large　vehicle　and　light-duty　vehicle　and　gas　station　respectively.