As　an　emerging　clean　technology,　the　replacement　of　coal　plants　and　the　integration　with　renewable　power　generation　are　two　appealing　options　for　the　deployment　of　SMRs　in　the　power　system.　However,　both　these　applications　and　SMR　siting　issues　for　power　systems　have　multiple　complexities　that　have　been　difficult　to　be　considered　in　past　studies.　Accordingly,　an　optimization-aided　small　modular　reactor　siting　(OASS)　model　is　initiated　in　this　study　to　support　decisions　of　siting,　sizing,　and　timing　for　small　modular　reactor　(SMR)　development.　The　proposed　OASS　model　is　specialized　for　obtaining　possible　SMRs　siting　schemes,　wind-SMRs　combination　schemes,　and　power　system　transition　schemes　with　coal　plant　closure　and　SMRs　deployment.　This　research　initiates　the　application　of　an　optimization-based　modelling　approach　to　tackle　SMRs　site　selection　issues　for　Saskatchewan,　Canada.　The　results　disclose　that　electricity　imports　and　natural　gas　power　will　fill　the　electricity　demand　gap　in　Saskatchewan＇s　power　system　in　the　short　term.　Results　obtained　from　this　model　can　also　identify　optimized　patterns　of　SMRs　and　wind　farms　deployment　and　siting　in　Saskatchewan.　Power　stations　with　large　capacity　and　independent　transmission　grid　will　become　the　primary　choice　in　the　SMRs　and　wind　farms　site　selection　process.　Such　patterns　and　alternatives　would　enable　decision-makers　obtain　optimized　energy　structure　by　introducing　SMR　reflecting　trade-offs　between　overall　system　costs　and　greenhouse　gas　(GHG)　emissions　from　both　economic　and　environmental　perspectives.