Bimetallic　compounds　are　a　kind　of　important　catalytic　materials　in　heterogeneous　catalysis.　In　this　work,　we　first　employed　n-butyllithium　as　reducing　agent　to　synthesize　Ir　and　IrFex　(x　is　the　Fe/Ir　molar　ratio　and　equal　to　0.49,　0.90,　and　2.80)　nanocrystals　(NCs),　and　then　used　an　adsorption　strategy　to　load　them　on　the　surface　of　ordered　mesoporous　ceria　(meso-CeO2)　derived　from　the　KIT-6-templating　route　to　obtain　the　0.48　wt%　Ir/mesoCeO2　(denoted　as　0.48Ir/meso-CeO2)　and　0.53-0.89　wt%　IrFex/meso-CeO2　(denoted　as　0.53IrFe0.49/meso-CeO2,　0.59IrFe0.90/meso-CeO2,　and　0.89IrFe2.80/meso-CeO2)　samples.　Physicochemical　properties　of　the　samples　were　characterized　by　means　of　various　techniques.　It　is　shown　that　all　of　the　samples　possessed　a　cubic　crystal　phase,　an　ordered　mesoporous　architecture,　and　a　surface　area　of　84-124　m2/g,　in　which　the　IrFex　NCs　with　an　average　size　of　ca.　2　nm　were　highly　dispersed　on　the　meso-CeO2　surface.　Among　all　of　the　samples,　0.59IrFe0.90/mesoCeO2　performed　the　best　for　acetylene　combustion　(T10%　=155　degrees　C,　T50%　=162　degrees　C,　and　T90%　=165　degrees　C　at　space　velocity　=　20,000　mL/(g　h)).　Furthermore,　0.59IrFe0.90/meso-CeO2　showed　good　water-　and　carbon　dioxideresistant　performance,　and　its　partial　deactivation　due　to　the　introduction　of　SO2　was　reversible.　The　possible　reaction　mechanisms　over　Ir/meso-CeO2　or　IrFex/meso-CeO2　were　also　discussed.　We　conclude　that　the　well　dispersed　IrFe0.90　NCs,　high　adsorbed　oxygen　and　acetylene　amounts,　low-temperature　reducibility,　and　strong　interaction　between　IrFe0.90　NCs　and　meso-CeO2　were　responsible　for　the　good　catalytic　performance　of　0.59IrFe0.90/meso-CeO2.