This　paper　is　an　attempt　to　investigate　optimal　routing,　aborting　and　hitting　strategies　of　Unmanned　Aerial　Vehicles　(UAVs)　executing　hitting　tasks.　Several　factors　such　as　time　window　and　a　certain　circular　defense　range　of　each　target,　the　optimal　bomb　and　fuel　loads　are　considered　in　the　UAVs　routing　plan　in　order　to　better　assign　targets　to　each　UAV　and　determine　the　hitting　order.　It　is　assumed　that　UAVs　may　be　attacked　by　random　shocks　when　they　are　within　the　target＇s　defense　range,　so　each　UAV　can　choose　to　abort　its　task　according　to　the　number　of　targets　that　the　UAV　has　hit　and　the　number　of　shocks　that　UAV　has　suffered　in　order　to　reduce　the　probability　of　UAVs　being　destroyed.　In　addition,　we　try　to　accomplish　two　objectives　simultaneously　with　meeting　the　fuel　requirements　and　increasing　the　probability　of　target　being　destroyed　by　optimizing　the　load　of　fuel　and　bomb.　The　tabu　search　algorithm　is　adopted　in　the　optimization　of　UAV　routing,　aborting　and　hitting　strategies,　and　numerical　experiments　are　presented　to　illustrate　the　performance　of　the　algorithm.