As　a　kind　of　environmentally　benign　reagents,　alpha-keto　acids　have　been　extensively　employed　as　key　starting　materials　in　organic　synthesis.　Organic　electrosynthesis　has　the　advantages　of　reducing　byproduct　generation,　improving　the　cost-efficiency　of　synthetic　processes,　and　accessing　reactive　intermediates　under　mild　conditions.　Inspired　by　the　merits　of　organic　electrosynthesis,　alpha-keto　acids　have　shown　many　synthetic　applications　in　electrochemical　acylation,　cyclization,　and　reductive　amination　reactions　with　improved　efficiencies　and　selectivities.　This　review　covers　the　recent　breakthroughs　achieved　in　the　electrochemical　transformations　of　alpha-keto　acids,　aimed　at　highlighting　these　electrochemical　reactions＇　features　and　mechanistic　rationalisations.　Meanwhile,　the　practicalities　and　limitations　of　these　transformations　are　also　presented　where　possible.　(C)　2021　Chinese　Chemical　Society　and　Institute　of　Materia　Medica,　Chinese　Academy　of　Medical　Sciences.　Published　by　Elsevier　B.V.　All　rights　reserved.